Transdiagnostic Associations between Anger Hostility and Chemokine Interferon-gamma Inducible Protein 10

Inducible Expression of Human Gamma Interferon

Background:The premature termination of high producer clones, which will be killed due to cell proliferation and proteins production antagonism, is one of the basic drawback in recombinant proteins technology. Furtheremore, it is supposed some toxic proteins like interferon which we intended to clone and express, inhibit host cells’ proliferation. So, it is necessary to tightly control IFN-γ pr...

Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction.

RATIONALE Interferon-gamma-inducible protein (IP)-10/CXCL10, an angiostatic and antifibrotic chemokine with an important role in T-cell trafficking, is markedly induced in myocardial infarcts, and may regulate the reparative response. OBJECTIVE To study the role of IP-10 in cardiac repair and remodeling. METHODS AND RESULTS We studied cardiac repair in IP-10-null and wild-type (WT) mice und...

Secretion of biologically active interferon-gamma inducible protein-10 (IP-10) by Lactococcus lactis

BACKGROUND Chemokines are a large group of chemotactic cytokines that regulate and direct migration of leukocytes, activate inflammatory responses, and are involved in many other functions including regulation of tumor development. Interferon-gamma inducible-protein-10 (IP-10) is a member of the C-X-C subfamily of the chemokine family of cytokines. IP-10 specifically chemoattracts activated T l...

Biochemical characterization of a gamma interferon-inducible cytokine (IP-10)

An IFN-gamma-inducible protein, IP-10, has previously been described to belong to a gene family of chemotactic and mitogenic proteins, associated with inflammation and proliferation. Biochemical characterization of this predicted protein has been pursued through the development of polyclonal monospecific antisera to recombinant protein and synthetic peptides. These reagents establish that the I...

Induction of the CXC Chemokine Interferon- –Inducible Protein 10 Regulates the Reparative Response Following Myocardial Infarction